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Contribution of Modern Echocardiographic Techniques in the Detection of Subclinical Heart Dysfunction in Young Adults with Non-Alcoholic Fatty Liver Disease.

Authors :
MOISE, CRISTIANA GIANINA
DONOIU, IONUȚ
TÂRTEA, GEORGICĂ-COSTINEL
MIREA, OANA
ROGOVEANU, ION
Source :
Current Health Sciences Journal. Apr-Jun2021, Vol. 47 Issue 2, p275-283. 9p.
Publication Year :
2021

Abstract

Non-alcoholic fatty liver disease affects about 30% of the population and it has a growing tendecy with the increasing incidence of obesity. Currently, a large amount of clinical evidence has shown that cardiovascular disease represents the main cause of mortality in patients suffering from non-alcoholic fatty liver disease. Objective: In this study we investigated the structural and functional changes of the left ventricle in young adults with hepatic steatosis using modern echocardiographic techniques. Methods:By using tissue Doppler imaging and also Speckle tracking echocardiography the left ventricle systolic function was assessed. Results: All patients included in the study had a normal left ventricular ejection fraction but, when the longitudinal function of the left ventricle was assessed using the tissue Doppler technique (maximum systolic velocity S) statistically significant differences were found in both the group of patients with non-alcoholic fatty liver as well as in the group of patients associated with diabetes. Using speckle tracking echocardiography, we found a statistically significant decrease of the global longitudinal strain in the endocardium, in the group of patients with non-alcoholic liver disease but also in the group of those with diabetes. The overall longitudinal strain at the myocardium was significantly reduced only in the group of patients with non-alcoholic fatty liver disease and diabetes, while the overall longitudinal strain at the epicardium showed no changes in any of the groups studied. Also, no changes were observed at the circumferential strain. Conclusion: Nonalcoholic fatty liver disease, diagnosed in asymptomatic young adults may be a risk factor for remodeling the left ventricle over time, being associated with subclinical myocardial dysfunction, regardless of the presence of other cardiovascular risk factors. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20670656
Volume :
47
Issue :
2
Database :
Academic Search Index
Journal :
Current Health Sciences Journal
Publication Type :
Academic Journal
Accession number :
152196689
Full Text :
https://doi.org/10.12865/CHSJ.47.02.19