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Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation.

Authors :
Frederiks, Aaron J
Creeper, Katherine J
Spagnolo, Dominic V
Cannell, Paul
Radeski, Dejan
Source :
Australasian Journal of Dermatology. Aug2021, Vol. 62 Issue 3, pe400-e403. 4p. 2 Color Photographs.
Publication Year :
2021

Abstract

We report the case of a 59‐year‐old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T‐cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00048380
Volume :
62
Issue :
3
Database :
Academic Search Index
Journal :
Australasian Journal of Dermatology
Publication Type :
Academic Journal
Accession number :
152095636
Full Text :
https://doi.org/10.1111/ajd.13606