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Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial.

Authors :
Knee, Jackie
Sumner, Trent
Adriano, Zaida
Anderson, Claire
Bush, Farran
Capone, Drew
Casmo, Veronica
Holcomb, David
Kolsky, Pete
MacDougall, Amy
Molotkova, Evgeniya
Braga, Judite Monteiro
Russo, Celina
Schmidt, Wolf Peter
Stewart, Jill
Zambrana, Winnie
Zuin, Valentina
Nalá, Rassul
Cumming, Oliver
Brown, Joe
Source :
eLife. 5/14/2021, p1-63. 63p.
Publication Year :
2021

Abstract

We conducted a controlled before-and-after trial to evaluate the impact of an onsite urban sanitation intervention on the prevalence of enteric infection, soil transmitted helminth reinfection, and diarrhea among children in Maputo, Mozambique. A non-governmental organization replaced existing poor-quality latrines with pour-flush toilets with septic tanks serving household clusters. We enrolled children aged 1-48 months at baseline and measured outcomes before and 12 and 24 months after the intervention, with concurrent measurement among children in a comparable control arm. Despite nearly exclusive use, we found no evidence that intervention affected the prevalence of any measured outcome after 12 or 24 months of exposure. Among children born into study sites after intervention, we observed a reduced prevalence of Trichuris and Shigella infection relative to the same age group at baseline (<2 years old). Protection from birth may be important to reduce exposure to and infection with enteric pathogens in this setting. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
2050084X
Database :
Academic Search Index
Journal :
eLife
Publication Type :
Academic Journal
Accession number :
152068500
Full Text :
https://doi.org/10.7554/eLife.62278