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Traumatic Brain Injury–Related Pediatric Mortality and Morbidity in Low- and Middle-Income Countries: A Systematic Review.
- Source :
-
World Neurosurgery . Sep2021, Vol. 153, p109-109. 1p. - Publication Year :
- 2021
-
Abstract
- The burden of pediatric traumatic brain injury (pTBI) in low- and middle-income countries (LMICs) is unknown. To fill this gap, we conducted a review that aimed to characterize the causes of pTBI in LMICs, and their reported associated mortality and morbidity. A systematic review was conducted. MEDLINE, Embase, Global Health, and Global Index Medicus were searched from January 2000 to May 2020. Observational or experimental studies on pTBI of individuals aged between 0 and 16 years in LMICs were included. The causes of pTBI and morbidity data were descriptively analyzed, and case fatality rates were calculated. PROSPERO ID: CRD42020171276. A total of 136 studies were included. Fifty-seven studies were at high risk of bias. Of the remaining studies, 170,224 cases of pTBI were reported in 32 LMICs. The odds of having a pTBI were 1.8 times higher (95% confidence interval, 1.6–2.0) in males. The odds of a pTBI being mild were 4.4 times higher (95% confidence interval, 1.9–6.8) than a pTBI being moderate or severe. Road traffic accidents were the most common cause (n = 16,275/41,979; 39%) of pTBIs. On discharge, 24% of patients (n = 4385/17,930) had a reduction in their normal mental or physical function. The median case fatality rate was 7.3 (interquartile range, 2.1–7.7). Less than a quarter (n = 32) of all LMICs have published high-quality data on the volume and burden of pTBI. From the limited data available, young male children are at a high risk of pTBIs in LMICs, particularly after road traffic accidents. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MIDDLE-income countries
*DEATH rate
*BRAIN injuries
*PHYSICAL mobility
*MORTALITY
Subjects
Details
- Language :
- English
- ISSN :
- 18788750
- Volume :
- 153
- Database :
- Academic Search Index
- Journal :
- World Neurosurgery
- Publication Type :
- Academic Journal
- Accession number :
- 152003663
- Full Text :
- https://doi.org/10.1016/j.wneu.2021.06.077