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Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative.
- Source :
-
Nature Reviews Nephrology . Sep2021, Vol. 17 Issue 9, p605-618. 14p. - Publication Year :
- 2021
-
Abstract
- Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes, including increased risk of chronic kidney disease, cardiovascular events and death. Risk factors for PO-AKI include older age and comorbid diseases such as chronic kidney disease and diabetes mellitus. PO-AKI is best defined as AKI occurring within 7 days of an operative intervention using the Kidney Disease Improving Global Outcomes (KDIGO) definition of AKI; however, additional prognostic information may be gained from detailed clinical assessment and other diagnostic investigations in the form of a focused kidney health assessment (KHA). Prevention of PO-AKI is largely based on identification of high baseline risk, monitoring and reduction of nephrotoxic insults, whereas treatment involves the application of a bundle of interventions to avoid secondary kidney injury and mitigate the severity of AKI. As PO-AKI is strongly associated with long-term adverse outcomes, some form of follow-up KHA is essential; however, the form and location of this will be dictated by the nature and severity of the AKI. In this Consensus Statement, we provide graded recommendations for AKI after non-cardiac surgery and highlight priorities for future research. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17595061
- Volume :
- 17
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Nature Reviews Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 151934053
- Full Text :
- https://doi.org/10.1038/s41581-021-00418-2