Clotiapine Toxicosis in a Puppy.

A 3.5-month-old, 1.5 kg Shih-Tzu puppy ingested 120mg of clotiapine - a neuroleptic drug used for treatment of schizophrenia in human medicine. Upon presentation the dog was mentally depressed, flaccid, with miotic pupils and a supraventricular tachycardia. It was treated with gastric lavage and supportive care. The dog recovered uneventfully and was discharged within 48 hours. This is the first veterinary report describing the clinical manifestation of clotiapine intoxication in a dog. [ABSTRACT FROM AUTHOR]