Orthostatic intolerance with Klippel-Trenaunay syndrome.

PROS includes, but is not limited to, KTS, CLOVES (congenital lipomatous overgrowth, vascular malformations, epidermal nevi, scoliosis/skeletal and spine syndrome), and megalencephaly-capillary malformation. Klippel-Trenaunay syndrome (KTS) is a genetic condition belonging to PIK3CA-related overgrowth spectrum (PROS) [[3]]. MR angiogram of the torso and legs revealed numerous venous varicosities in the right gluteal and thigh muscle groups as well as a large ectatic vein in the distal lateral thigh. Keywords: Orthostatic intolerance; PIK3CA-related overgrowth spectrum; Klippel-Trenaunay syndrome; Postural tachycardia EN Orthostatic intolerance PIK3CA-related overgrowth spectrum Klippel-Trenaunay syndrome Postural tachycardia 577 579 3 07/22/21 20210801 NES 210801 Supplementary Information The online version contains supplementary material available at https://doi.org/10.1007/s10286-021-00791-9. [Extracted from the article]