Computational model of decreased suppression of mu rhythms in patients with Autism Spectrum Disorders during movement observation—preliminary findings.

Autism Spectrum Disorders (ASD) represent developmental conditions with deficits in the cognitive, motor, communication and social domains. It is thought that imitative behaviour may be impaired in children with ASD. The Mirror Neural System (MNS) concept plays an important role in theories explaining the link between action perception, imitation and social decision-making in ASD. In this study, Emergent 7.0.1 software was used to build a computational model of the phenomenon of MNS influence on motion imitation. Seven point populations of Hodgkin–Huxley artificial neurons were used to create a simplified model. The model shows pathologically altered processing in the neural network, which may reflect processes observed in ASD due to reduced stimulus attenuation. The model is considered preliminary—further research should test for a minimally significant difference between the states: normal processing and pathological processing. The study shows that even a simple computational model can provide insight into the mechanisms underlying the phenomena observed in experimental studies, including in children with ASD. [ABSTRACT FROM AUTHOR]