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Quantitative and Qualitative Approach for Shear Wave Elastography in Superficial Lymph Nodes.

Authors :
Chami, Linda
Giron, Alain
Ezziane, Malek
Leblond, Véronique
Charlotte, Frédéric
Pellot-Barakat, Claire
Lucidarme, Olivier
Source :
Ultrasound in Medicine & Biology. Aug2021, Vol. 47 Issue 8, p2117-2127. 11p.
Publication Year :
2021

Abstract

The diagnostic contribution of 2-D shear-wave elastography (SWE) in management of superficial lymph nodes (LNs) of any origin was evaluated in 222 patients referred for needle core biopsy. Each patient underwent conventional B-mode/Doppler ultrasound examinations (conventional ultrasound) and SWE. Quantitative SWE parameters and qualitative SWE map features were extracted. Carcinomas were found to be significantly stiffer than benign LNs (29.5 ± 32.3 kPa vs. 6.7 ± 12.3 kPa). Lymphomas exhibited intermediate stiffness (11.4 ± 5.2 kPa). Qualitative SWE analysis provided color patterns specific to histopathology (stiff rim, nodular and undetermined patterns related to malignancy and blue pattern to benignity). Adding SWE to conventional ultrasound improved the sensitivity of LN diagnosis (from 81.1% to 92.0%) but decreased its specificity (from 73.2% to 67.6%) because of the high prevalence of lymphomas compared with carcinomas. Inter-observer agreement for quantitative SWE was good (intra-class correlation coefficient = 0.82) as was inter-observer diagnostic agreement for qualitative SWE (κ = 0.65). LN location and histology type were found to influence the reported diagnostic performance of SWE. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03015629
Volume :
47
Issue :
8
Database :
Academic Search Index
Journal :
Ultrasound in Medicine & Biology
Publication Type :
Academic Journal
Accession number :
151123978
Full Text :
https://doi.org/10.1016/j.ultrasmedbio.2021.04.008