A Web-based Dose-volume Histogram Dashboard for Library-based Individualized Dose-constraints and Clinical Plan Evaluation.

Traditional methods of treatment planning and plan evaluation involve the use of generic dose-constraints. We aimed to build a web-based application to generate individualized dose-constraints and plan evaluation against a library of prior approved plan dose-volume histograms (DVH). A prototype was built for intensity modulated radiation therapy (IMRT) plans for prostate cancer. Using exported DVH files from the Varian and Accuray treatment planning systems, a library of plan DVHs was built by data extraction. Given structure volumes of a patient to be planned, a web based application was built to derive individual dose-constraints of the planning target volume (PTV) and organs-at-risk (OAR) based on achieved doses in a library of prior approved plans with similar anatomical volumes, selected using an interactive dashboard. A second web application was built to compare the achieved DVHs of the newly created plan against a library of plans of similar patients. These web application prototypes are a proof of principle that simple freely available tools can be built for library based planning and review. [ABSTRACT FROM AUTHOR]