Pyoderma gangrenosum as a cause of spontaneous vulvovaginal ulceration.

The article presents a case study regarding Pyoderma gangrenosum as a cause of spontaneous vulvovaginal ulceration. A 55-year-old woman was admitted to the hospital with spontaneous ulcerations of the vulva, vagina and the right gluteal region that had developed during the preceding week. The ulcerations developed rapidly as painful redness and infiltrations of the skin, followed by necrotization. She stated that "pieces of the skin fell off," resulting in deep and very painful ulcerations. Biopsies from the ulcer margin showed nonspecific changes with ulceration and neutrophilic infiltration without certain signs of vasculitis.