后路与前路手术内固定融合术对脊柱骨折患者脊柱功能及创伤应激指标的影响.

To investigate the effect of posterior and anterior internal fixation and fusion on spinal function and trauma stress index in patients with spinal fracture. 102 patients with spinal fracture in the Affiliated Hospital of Xuzhou Medical University from March 2015 to March 2019 were selected, they were divided into two groups: posterior group (n=52, posterior internal fixation and fusion) and anterior group (n=50, anterior internal fixation and fusion) according to the way of operation. The operative related indexes, trauma stress indexes, vertebral parameters, excellent rate of spinal function recovery and complications of the two groups were compared. The excellent and good recovery rate of spinal function in the posterior group was higher than that in the anterior group (P<0.05). The operation time, incision length and hospitalization time of the posterior group were shorter than those of the anterior group, and the amount of intraoperative bleeding was less than that of the anterior group (P<0.05). 6 months after operation, the height of anterior edge and posterior edge of vertebral body in the two groups increased, and that in the posterior group was higher than that in the anterior group (P<0.05), Cobb's angle decreased and the posterior group was lower than the anterior group (P<0.05). Adrenocorticotropic hormone (ACTH), tumor necrosis factor-α (TNF-α), cortisol (COR) were all increased in the two groups 2 weeks after operation, but they were lower in the posterior group than in the anterior group (P<0.05). The incidence of complications in the posterior group was lower than that in the anterior group (P<0.05). Compared with anterior internal fixation and fusion in the treatment of spinal fracture, posterior internal fixation and fusion can effectively improve the spinal function, reduce the incidence of traumatic stress and complications. [ABSTRACT FROM AUTHOR]