Severe obesity associated with hyperglycemia and abdominal fats in metabolic syndrome patients.

Background: Obesity is a major public problem in developed and developing countries associated with a high mortality rate. Herein, we determined the relationships between severe obesity, lipid profile, blood glucose in metabolic syndrome (MS) patients. Materials and Methods: In a cross-sectional 215 MS patients, ages ranged from 37 to 84 were randomly selected. Body mass index and waist circumference (WC) were estimated. Fasting serum lipid profile and plasma blood glucose were measured. Results: In total, 132 (61.4%) were female, 151 (70.2%) were obese, 64 (29.8%) were sever obese, and 143 (66.5%) had WC ≥ 110. Chi-square analyses show that severe obesity was significantly associated with increased WC and hyperglycemia with (odds ratio [OR] = 2.230 and 2.400) and (P = 0.019 and 0.005), respectively. The severe obesity in females was two-fold increased than males (OR = 1.93, P = 0.028). Conclusion: Severe obesity associated with central obesity and hyperglycemia in MS patients. Moreover, females at higher risk to have severe obesity. [ABSTRACT FROM AUTHOR]