心理因素对美沙酮维持治疗脱失的影响及对策研究.

Objective To study the influence of psychological factors on the loss of methadone maintenance treatment and its countermeasures, and to provide a basis for formulating corresponding intervention countermeasures. Methods From April 2012 to July 2013.a prospective cohort study was conducted to conduct a follow-up survey of patients in 6 methadone maintenance treatment clinics in Guangzhou. The basic information. psychological factors and other information of the treated person were collected. The national unified methadone maintenance treatment information collection system was used to collect daily medication records of patients. The Cox proportional hazards regression model was used to analyze the influencing factors of the loss of methadone maintenance treatment patients. Results Among the 548 subjects. 485(89. 2%) were male, and their age was (41.9±6. 5) years old. The one-year loss rate was 54. 7% (300/548). Multivariate Cox regression analysis found that among the psychological factors self efficacy (HR=0.97, P=0.005) was the main cause of loss. Conclusion The lower the self-efficacy, the easier it is to lose. In or der to reduce the loss rate.in addition to providing methadone, methadone clinics should also carry out appropriate psychological intervention services to improve patients' confidence in persisting in taking medication. [ABSTRACT FROM AUTHOR]