Synthesis of isoxazolylpyrrolones by three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes.

Authors :: Sakhno, Yana I.
Radchenko, Oleksandr V.
Muravyova, Elena A.
Sirko, Svitlana M.
Shishkina, Svitlana V.
Musatov, Vladimir I.
Desenko, Sergey M.
Chebanov, Valentyn A.
Source :: Chemistry of Heterocyclic Compounds. Mar2021, Vol. 57 Issue 3, p261-265. 5p.
Publication Year :: 2021
Abstract: [2-Aryl-4-hydroxy-1-(5-methylisoxazol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrol-3-yl]acetic acids and their esters were synthesized by the three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes. [ABSTRACT FROM AUTHOR]

Subjects :: *DIETHYL sulfate
*ACETIC acid
*ESTERS
*ACIDS
*AROMATIC aldehydes

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