Glucocorticoid-free treatment of severe ANCA-associated vasculitis.

The majority of patients (8/11) had kidney involvement, with 6 patients undergoing kidney biopsy to confirm this (Figure 1A). Two patients underwent an interval kidney biopsy to confirm histologic disease remission (Figure 1B). Eleven patients with active, organ-threatening AAV were treated without any oral or intravenous glucocorticoids (Table 1); six patients presented with de novo disease and five with relapse. Six patients had granulomatosis with polyangiitis (GPA) and five patients had microscopic polyangiitis. [Extracted from the article]