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Adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria.

Authors :
Mejia, Pedro
Treviño-Villarreal, J. Humberto
De Niz, Mariana
Meibalan, Elamaran
Longchamp, Alban
Reynolds, Justin S.
Turnbull, Lindsey B.
Opoka, Robert O.
Roussilhon, Christian
Spielmann, Tobias
Ozaki, C. Keith
Heussler, Volker T.
Seydel, Karl B.
Taylor, Terrie E.
John, Chandy C.
Milner, Danny A.
Marti, Matthias
Mitchell, James R.
Source :
Science Advances. 3/24/2021, Vol. 7` Issue 13, p1-11. 11p.
Publication Year :
2021

Abstract

The article presents findings of the study related to adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria. It mentions that circulating levels of the adipokine leptin are linked to neuropathology in experimental cerebral malaria. It discusses the potential implications for pathogenesis of malaria infection, prognosis, and treatment.

Details

Language :
English
ISSN :
23752548
Volume :
7`
Issue :
13
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
149584612
Full Text :
https://doi.org/10.1126/sciadv.abe2484