Back to Search
Start Over
Programming folding cooperativity of the dimeric i-motif with DNA frameworks for sensing small pH variations.
- Source :
-
Chemical Communications . 4/4/2021, Vol. 57 Issue 26, p3247-3250. 4p. - Publication Year :
- 2021
-
Abstract
- The response sensitivity of a molecular sensor is determined by the folding cooperativity of its responsive module. Using an H+-responsive dimeric DNA i-motif as a model, we demonstrate the enhancement of its folding cooperativity through preorganization by a DNA framework, and with it we fabricate robust intracellular pH sensors with high response sensitivity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DNA
*DETECTORS
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 57
- Issue :
- 26
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 149554703
- Full Text :
- https://doi.org/10.1039/d1cc00266j