Back to Search
Start Over
Acute hemodynamic effects of non-invasive ventilation in patients with obesity hypoventilation syndrome.
- Source :
-
Bratislava Medical Journal / Bratislavské Lekárske Listy . 2021, Vol. 122 Issue 4, p248-250. 3p. - Publication Year :
- 2021
-
Abstract
- OBJECTIVE: To evaluate the acute effects of volume-targeted non-invasive ventilation (NIV) on hemodynamic parameters assessed by impedance cardiography in patients with obesity hypoventilation syndrome (OHS). BACKGROUND: Despite the well-described beneficial effects of NIV using volume-targeted pressure support ventilation modes on respiration in OHS patients, questions were raised about the impact of this treatment on the cardiovascular system. METHODS: In 15 patients (10 men; mean age, 55.8±9.3 years) impedance cardiography recordings were taken at baseline, after 120 minutes while on NIV and 20 minutes after NIV termination. A repeated-measures analysis of variance was used for comparisons. RESULTS: Compared to baseline, a reduction in heart rate (from 80±11 to 73±10 beats per min, p<0.05) was observed on NIV whereas the stroke volume and cardiac index remained stable throughout all three assessed intervals (p=0.347, p=0.344; respectively). The pre-ejection period increased on NIV (from 113±16 to 127±20 ms, p<0.05), and the left ventricular ejection time increased after NIV termination compared to baseline (from 259±25 to 269±25 ms, p<0.05). CONCLUSION: Volume-targeted NIV may acutely improve systolic time intervals without any negative impact on the left ventricular function in OHS patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00069248
- Volume :
- 122
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Bratislava Medical Journal / Bratislavské Lekárske Listy
- Publication Type :
- Academic Journal
- Accession number :
- 149427858
- Full Text :
- https://doi.org/10.4149/BLL_2021_040