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Facile synthesis of nitrogen-doped carbon dots from pork liver and its sensing of 6-thioguanine based on the inner filter effect.
- Source :
-
New Journal of Chemistry . 3/21/2021, Vol. 45 Issue 11, p5114-5120. 7p. - Publication Year :
- 2021
-
Abstract
- In this work, a facile one-step hydrothermal method was developed to synthesize nitrogen-doped carbon dots (N-CDs) using pork liver. The quantum yield of the prepared N-CDs was as high as 11.74%. The excitation and emission wavelengths of the N-CDs were 329 and 410 nm, respectively. The excitation spectrum of the N-CDs has a big overlap with the absorption band of 6-thioguanine (6-TG), which formed an inner filter effect (IFE) between them. 6-TG acted as an effective absorber in IFE to quench the fluorescence of the N-CDs. The concentration of 6-TG was well linear with the fluorescence quenching intensity of the system from 1 μM to 200 μM. The limit of detection was as low as 0.75 μM. This proposed method was successfully applied in selective and sensitive determination of 6-TG in human serum with recoveries of 96.2–105.3%. [ABSTRACT FROM AUTHOR]
- Subjects :
- *FLUORESCENCE quenching
*EXCITATION spectrum
*CARBON
*DETECTION limit
*PORK
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 45
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 149410461
- Full Text :
- https://doi.org/10.1039/d0nj05483f