EUCAST rapid antimicrobial susceptibility testing of blood cultures positive for Escherichia coli or Klebsiella pneumoniae: experience of three laboratories in Italy.

We herein report on EUCAST RAST results for BCs consecutively collected between June 2019 and December 2019 that contained E. coli (n" 134) or K. pneumoniae (n" 66) isolates (Table S1, available as Supplementary data at JAC Online), of which 75 (37.5%) were phenotypically resistant to third-generation cephalosporins and/or carbapenems. In conclusion, we showed that the EUCAST RAST method affords an accurate and relatively easy means of testing antimicrobial susceptibility of E. coli and K. pneumoniae isolates directly in positive BC samples. Note that we tested only BC samples containing E. coli or K. pneumoniae, which are two species for which all DD plates could be read at the three timepoints. [Extracted from the article]