无水乙醇联合聚桂醇治疗下肢静脉畸形的疗效分析.

Objective To explore the efficacy and complications of absolute ethanol combined with lauromacrogol in the treatment of venous malformations in lower limbs. Methods The clinical data of 27 patients with venous malformations in the lower limbs from July 2015 to July 2019 were retrospectively analyzed. According to the ages and tumors, the absolute ethanol and lauromacrogol were selected for multiple sclerotherapy. The average treatment of absolute ethanol was (2.59±2.19) /case, and the average single dose was (0.18 ± 0.04) ml/kg. The average treatment of lauromacrogol foam sclerosing agent was (3.30±2.57)/case, and the average single dose was (8.45 ± 3.10) ml. All patients were followed-up for 3 months to 2 years, the efficacy and complications were observed. Results In 27 patients, the symptoms were obviously improved and the tumor size was reduced. No recurrence was found. The average pain scores based on Wong-Banker face pain scale-revised (FPS-R) was (0.44 ± 0.85), which was significantly lower than that before the operation of (3.04 ± 1.23). The symptoms of patients were significantly improved. The main complications including swelling (100%), pain (100%), pigmentation (14.4%), blisters (7.4%) and skin ulcers (3.7%). Conclusion The efficacy of absolute ethanol combined with lauromacrogol foam sclerosing agent in the treatment of venous malformations in lower limbs was obvious. The safety of treatment was also improved. [ABSTRACT FROM AUTHOR]