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Glucocorticoid counteracts cellular mechanoresponses by LINC01569-dependent glucocorticoid receptor-mediated mRNA decay.

Authors :
Huayu Zhu
Jun Li
Yize Li
Zhao Zheng
Hao Guan
Hongtao Wang
Ke Tao
Jiaqi Liu
Yunchuan Wang
Wanfu Zhang
Chao Li
Jie Li
Lintao Jia
Wendong Bai
Dahai Hu
Source :
Science Advances. 2/24/2021, Vol. 7 Issue 9, p1-18. 18p.
Publication Year :
2021

Abstract

The article offers information on a study that explores about the glucocorticoid counteracts cellular mechanoresponses by LINC01569-dependent glucocorticoid receptor–mediated mRNA decay. It mentions the roles of glucocorticoid in cellular mechano transduction and novel lncRNA-dependent GMD machinery and provided potential strategy for early intervention in mechanical disorder–associated diseases.

Details

Language :
English
ISSN :
23752548
Volume :
7
Issue :
9
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
149063774
Full Text :
https://doi.org/10.1126/sciadv.abd9923