Definitions for coronavirus disease 2019 reinfection, relapse and PCR re-positivity.

SARS-CoV-2 RT-PCR re-positivity SARS-CoV-2 RT-PCR re-positivity describes positive RT-PCR following negative tests in an asymptomatic patient up to 90 days from the first episode. Keywords: COVID-19; PCR re-positivity; Reinfection; Relapse EN COVID-19 PCR re-positivity Reinfection Relapse 315 318 4 03/03/21 20210301 NES 210301 Introduction Defining reinfection, relapsed infection and recurrence of positive (re-positive) nucleic acid detection might have clinical and epidemiological implications for treatment and infection control measures, respectively. (b) Proof of a reinfection with two positive SARS-CoV-2 RT-PCR tests with Ct < 35 (or proof of replicating virus by cell culture or detection of subgenomic RNA) at different time-points. COVID-19 reinfection In August 2020, To et al. described an asymptomatic patient from Hong Kong with a positive SARS-CoV-2 PCR test from a sample collected 142 days after a first symptomatic COVID-19 episode. [Extracted from the article]