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Imidazolium ylide mediated tandem Knoevenagel–Michael–O-cyclization sequence for the synthesis of multi-substituted 4,5-dihydrofurans.

Authors :
Sathiyamoorthi, Sivakumar
Almansour, Abdulrahman I.
Raju, Suresh Kumar
Natarajan, Arumugam
Kumar, Raju Ranjith
Source :
Synthetic Communications. 2021, Vol. 51 Issue 2, p234-244. 11p. 6 Diagrams, 1 Chart.
Publication Year :
2021

Abstract

The stereoselective syntheses of novel trans-5-aroyl-2,4-diaryl-4,5-dihydrofuran-3-carbonitriles have been achieved via a one-pot, three-component tandem protocol involving aroyl acetonitriles, aromatic aldehydes, and imidazolium ylide in the presence of Et3N. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*ACETONITRILE
*AROMATIC aldehydes

Details

Language :
English
ISSN :
00397911
Volume :
51
Issue :
2
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
148480811
Full Text :
https://doi.org/10.1080/00397911.2020.1821226