Novel synthetic approach to pyrrolo[1,2-b]cinnolines.

Authors :: Plieva, Anastasia T.
Chalikidi, Petrakis N.
Gutnov, Andrey V.
Turiev, Anatolij M.
Demidov, Oleg P.
Aksenov, Nicolai A.
Magkoev, Taimuraz T.
Abaev, Vladimir T.
Source :: Chemistry of Heterocyclic Compounds. 2020, Vol. 56 Issue 8, p1030-1041. 12p.
Publication Year :: 2020
Abstract: Straightforward method for the synthesis of pyrrolo[1,2-b]cinnolines starting from 2-nitrobenzaldehydes and 2-methylfurans has been elaborated. The key steps of the process are oxidative furan ring opening with diazonium cation and intramolecular alkylation of azo group of the resulted cinnoline with secondary allyl alcohol. [ABSTRACT FROM AUTHOR]