ETIOLOGY OF LIVER CIRRHOSIS IN DISTRICT BUNER, KHYBER PAKHTUNKHWA.

Objective: The aim of our study was to determine the most common cause of liver cirrhosis in district Buner. Material and Method: This was retrospective data review of patients record. Data was collected from patient's record register from January 2016 till December 2018. A total of 203 patients were included in this study. Data was collected and entered and analyzed in IBM SPSS 23. Results: Out of 203 cases, 135(66.5%) were males and 68 (33.5%) were females. The main cause of cirrhosis was HCV (n=163, 80.3%) and HBV (n=27, 13.3%). Cryptogenic cirrhosis occurred in 9 cases (4.4%) while others were only 1% (n=2). HCV positivity was more in males (n=108, 66.25%) than in females (n=55, 33.7%) with a p value .022. Conclusion: HCV is major cause of Liver Cirrhosis in our patients. HCV is more common in males than in females. Cirrhosis occurs most commonly in 4th, 5th and 6th decades of life after being infected with HBV and HCV. [ABSTRACT FROM AUTHOR]