重症急性胰腺炎患者生存质量调查及并发腹腔感染的影响因素分析.

Objective: To investigate the quality of life of patients with severe acute pancreatitis (SAP), and to analyze the influencing factors of SAP complicated with abdominal infection. 136 patients with SAP in our hospital from January 2017 to December 2019 were selected and included in the study group. Another 90 volunteers who had physical examination in our hospital at the same time were selected as the control group. The patients in the study group were divided into infection group (n=48) and non infection group (n=88) according to the abdominal infection situation. Quality of life survey (SF-36) was used to evaluate the quality of life of the control group and the study group. The influencing factors of SAP complicated with abdominal infection were analyzed by univariate and multivariate logistic regression. The scores of social function, energy, physiological function, emotional function, physiological function, general health condition, physical pain and mental health of the study group were lower than those of the control group (P<0.05). Univariate analysis showed that mechanical ventilation time, multiple organ dysfunction syndrome, diabetes mellitus, hypoxemia, intestinal dysfunction time, renal failure, Acute physiology and chronic health status score II (APACHE Ⅱ) were associated with SAP complicated with abdominal infection (P<0.05), but not with gender, age, type of disease, etiology and respiratory failure (P>0.05). Multivariate Logistic regression analysis showed that multiple organ dysfunction syndrome, mechanical ventilation time≥ 10 h, intestinal dysfunction time≥ 4 d, renal failure, hypoxemia, APACHE Ⅱ>11 points were independent risk factors of SAP complicated with abdominal infection (P<0.05). Compared with healthy patients, patients with SAP have a lower quality of life and required continuous health intervention outside the hospital. In addition, SAP complicated with abdominal infection is associated with many factors, which should be paid attention to clinically and relevant countermeasures should be taken actively to improve the prognosis of patients. [ABSTRACT FROM AUTHOR]