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Levodopa-responsive progressive encephalomyelitis with rigidity and myoclonus associated with glycine receptor antibodies.

Authors :
Sturchio, Andrea
Gastaldi, Matteo
Cariddi, Lucia Princiotta
Biacchi, Daniela
Espay, Alberto J.
Franciotta, Diego
Versino, Maurizio
Mauri, Marco
Source :
Parkinsonism & Related Disorders. Jan2021, Vol. 82, p7-9. 3p.
Publication Year :
2021

Abstract

• New dopa-responsive phenotype expands the spectrum of GlyR antibody-associated PERM syndrome. • Appendicular rigidity with axial hypotonia and oculomotor abnormalities suggested hypodopaminergic tone. • Downstream effects GlyR antibody may interfere with the dopamine network. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*GLYCINE receptors
*RECEPTOR antibodies
*ENCEPHALOMYELITIS
*MYOCLONUS
*PHENOTYPES
*DOPA
*ENCEPHALITIS
*AUTOANTIBODIES
*NEUROLOGICAL disorders
*COMBINATION drug therapy
*ORGANIC compounds
*CELL receptors
*AUTOIMMUNE diseases
*MUSCLE rigidity
*DOPAMINE agents
*PHARMACODYNAMICS

Details

Language :
English
ISSN :
13538020
Volume :
82
Database :
Academic Search Index
Journal :
Parkinsonism & Related Disorders
Publication Type :
Academic Journal
Accession number :
147964625
Full Text :
https://doi.org/10.1016/j.parkreldis.2020.11.008
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