Methadone: Drug dependence following abuse and neonatal abstinence syndrome following in-utero exposure: 2 case reports.

B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A female patient [ I age not stated i ] developed drug dependence following methadone abuse during pregnancy. Subsequently, her female neonate [ I exact age not stated i ] developed neonatal abstinence syndrome (NAS) following I in utero i exposure of methadone [ I times to reactions onsets not stated; not all routes and outcomes stated i ]. [Extracted from the article]