Location location location: muscle glycogen content and endurance exercise.

Keywords: dietary carbohydrate; muscle homogenate; single fibre; subcellular localisation EN dietary carbohydrate muscle homogenate single fibre subcellular localisation 19 21 3 01/04/21 20210101 NES 210101 Muscle glycogen and endurance exercise The percutaneous muscle biopsy technique was developed in Sweden in the 1960s and spawned a decade of revelatory investigations on the interaction between diet, exercise and muscle glycogen. As expected, pre-exercise whole-muscle glycogen content was different between all sessions (HIGH > MIXED > LOW) and was directly associated with performance times, with greater muscle glycogen pre-exercise associated with greater time-to-exhaustion. Although pre-exercise glycogen content in all locations was associated with exercise performance, pre-exercise content of intermyofibrillar and subsarcolemmal glycogen more strongly correlated with time-to-exhaustion than intramyofibrillar glycogen, while this association was inverted following 60 min of exercise. [Extracted from the article]