Autonomic response after hemorrhagic stroke in the right insular cortex: What is the common pathophysiology in rat and human?

Keywords: Insular cortex; Hemorrhagic stroke; Autonomic nervous system; Laterality; Central autonomic network EN Insular cortex Hemorrhagic stroke Autonomic nervous system Laterality Central autonomic network N.PAG N.PAG 1 12/29/20 20210101 NES 210101 We read the interesting study by [5], who reported the autonomic and cardiovascular consequences resulting from an experimental intracerebral hemorrhage (ICH) stroke in the left or right intermediate insular cortex (Ic) in rats. The hypoactivity in the patient's left Ic due to the chronic left ICA occlusion might have led to a decrease in parasympathetic autonomic nervous activity, and to a shift in the sympathovagal balance toward a predominant SNS tone. [Extracted from the article]