Indium(I)/CuFe2O4 Reagent for Allylation of Carbonyls and Epoxide Rearranged Carbonyls.

Indium(I)/CuFe2O4 reagent for carbonyl allylation and epoxide rearranged carbonyl allylation is proposed for formation of homoallylic alcohols. The In(I) reagent in combination with catalytic amount of CuFe2O4 support in situ formation of nucleophilic allylic indium from allyl halide in THF medium. Nucleophilic allylic indium species react with carbonyls to form homoallyl alcohols in good to excellent yields. Under the presented reaction conditions arylepoxides undergo smooth rearrangement into aldehydes that are also allylated with formation of homoallyl alcohols. The process is highly efficient and tolerates different functional groups. [ABSTRACT FROM AUTHOR]