血浆置换及血小板输注治疗特发性血小板减少性紫癜疗效观察.

Objective: To explore the therapeutic effect of plasma exchange and platelet transfusion on idiopathic thrombocytopenic purpura. Methods: 60 patients with idiopathic thrombocytopenic purpura who were treated in our hospital from February 2016 to January 2019 were selected as the research object, and they were divided into platelet transfusion group (20 cases) and plasma according to the difference in treatment options In the Plasma exchange (PE) group (40 cases), the treatment efficiency, changes in blood cell counts before and after treatment, and the occurrence of various adverse reactions during treatment were compared between the two groups. Results: In the platelet transfusion group, there were 10 cases of effective treatment, 6 effective cases, and the total effective rate was 80.00 %. In the PE group, there were 27 cases of effective treatment, 12 effective cases, and the total effective rate was 97.50 %. The difference is obvious(P<0.05). Compared with before treatment, the PLT, RBC count and Hb levels of PE patients increased significantly, the WBC count decreased significantly (P<0.05), and the PLT, RBC count and Hb levels of platelet transfusion group also increased significantly High, the WBC count level decreased (P<0.05), but the comparison between the groups showed that the above indexes of the PE group after treatment were better than the platelet transfusion group (P<0.05). The total number of adverse reactions in the platelet transfusion group was 4 and the total incidence of adverse reactions was 20.00%. The total number of adverse reactions in the PE group was 3 and the total incidence of adverse reactions was 7.50%. Lower than platelet transfusion group (P<0.05). Conclusion: Platelet transfusion and plasma exchange have a good therapeutic effect on idiopathic thrombocytopenic purpura, which can significantly improve the patient's abnormal blood cell count, but plasma exchange treatment is more safe. [ABSTRACT FROM AUTHOR]