Back to Search
Start Over
Linear transformations extract parameters of ionic currents and action potential features from pseudo-ECG in cardiomyocyte models.
- Source :
-
AIP Conference Proceedings . 2020, Vol. 2316 Issue 1, p1-5. 5p. - Publication Year :
- 2020
-
Abstract
- Pseudo electrocardiogram (pseudo-ECG) is a virtual ECG signal that is computed using 1D mathematical models of the myocardium. This signal has the QRS-complex and T wave similar to that of real ECG. In this paper, we used pseudo-ECG as a tool to develop an algorithm for the estimation of electrophysiological properties of the myocardium or single cardiomyocytes based on electrogram recordings. Here, we analyzed the relationship between pseudo-ECG produced by a 1D myocardial model and characteristics of the cellular action potential and parameters of an ionic cardiomyocyte model. We showed that in the noise-free conditions the action potential morphology and cardiomyocyte model parameters can be identified from pseudo-ECG using a linear transformation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MYOCARDIUM
*ELECTROPHYSIOLOGY
*ALGORITHMS
*MATHEMATICAL models
*ELECTROCARDIOGRAPHY
Subjects
Details
- Language :
- English
- ISSN :
- 0094243X
- Volume :
- 2316
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- AIP Conference Proceedings
- Publication Type :
- Conference
- Accession number :
- 147606603
- Full Text :
- https://doi.org/10.1063/5.0035269