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Microfluidic-based liquid-liquid microextraction in combination with smartphone-based on-chip detection for the determination of copper in biological, environmental, and food samples.

Authors :
Shahvar, Ali
Shamsaei, Danial
Saraji, Mohammad
Arab, Negin
Alijani, Shekoufeh
Source :
Microchemical Journal. Jan2021:Part A, Vol. 160, pN.PAG-N.PAG. 1p.
Publication Year :
2021

Abstract

• Microfluidic-based microextraction was combined with smartphone-based detection. • An on-chip sensing strategy was introduced using a smartphone. • The copper assay was performed by the method successfully. • The method was used for the analysis of biological, environmental, and food samples. • The method was simple and cost-effective with adequate analytical performance. In the present work, a simple and green microfluidic-based liquid-liquid microextraction in combination with smartphone-based on-chip detection was introduced for the determination of copper in environmental, biological, and food samples. The procedure was based on an ion-pair formation between tetrabutylammonium and tetrathiocyanatocuprate(II) anion, which was extracted with a suitable extractant and subsequent color sensing using a smartphone. All the steps were performed in a microchip. The smartphone was used as both a detector and a data processing unit. Different experimental parameters affecting analytical signal were studied and optimized. Under the optimum conditions, the method showed a linear dynamic range between 0.3 and 40 mg L−1 with a determination coefficient of 0.9953. The limits of detection and quantification were obtained 0.1 and 0.3 mg L−1, respectively. The method provided a precise determination with relative standard deviations in the range of 4.1–5.3%. Finally, the method was successfully applied for the determination of copper in whole blood, mushroom, wastewater, and tap water samples with spiking recoveries in the ranges of 80–98%, 96–108%, 95–107%, and 100–103%, respectively. In comparison with the atomic absorption technique, no significant difference was observed between the two methods in terms of accuracy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0026265X
Volume :
160
Database :
Academic Search Index
Journal :
Microchemical Journal
Publication Type :
Academic Journal
Accession number :
147406763
Full Text :
https://doi.org/10.1016/j.microc.2020.105655