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Dilation Modifies Association Between Symptoms and Esophageal Eosinophilia in Adult Patients With Eosinophilic Esophagitis.
- Source :
-
American Journal of Gastroenterology (Lippincott Williams & Wilkins) . Dec2020, Vol. 115 Issue 12, p2098-2102. 5p. - Publication Year :
- 2020
-
Abstract
- INTRODUCTION: We investigated whether dilation modifies the association between symptoms and esophageal eosinophilia (peak esophageal eosinophils/high-power field [eos/hpf]) in patients with eosinophilic esophagitis enrolled into a randomized trial comparing the efficacy of budesonide and fluticasone. METHODS: Baseline Dysphagia Symptom Questionnaire and Eosinophilic Esophagitis Activity Index were available in 102 and 73 patients, respectively, of whom 56 and 39 underwent dilation at screening endoscopy before symptom assessment. The pair-wise relationship between Dysphagia Symptom Questionnaire, Eosinophilic Esophagitis Activity Index, and eos/hpf was analyzed with nonparametric correlations. RESULTS: In nondilated patients, the association between baseline eos/hpf and symptoms was moderate and significant, although it was abolished in dilated patients. DISCUSSION: Dilation modifies association between symptoms and eos/hpf (clinicaltrials.gov NCT02019758). [ABSTRACT FROM AUTHOR]
- Subjects :
- *DILATATION & extraction abortion
*EOSINOPHILIA
*BUDESONIDE
*FLUTICASONE
*ENDOSCOPY
Subjects
Details
- Language :
- English
- ISSN :
- 00029270
- Volume :
- 115
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- American Journal of Gastroenterology (Lippincott Williams & Wilkins)
- Publication Type :
- Academic Journal
- Accession number :
- 147398173
- Full Text :
- https://doi.org/10.14309/ajg.0000000000000957