发现新型环境有机污染物的 基本理论与方法.

Since the twentieth century, the health hazards caused by chemical pollutants have become increasingly prominent. Tens of thousands of high throughput chemicals have entered into the environment along with the massive production and use, raising emerging scientific issues for research in environmental science related fields. In this article, background and scientific significance of establishing the research direction on identification of novel organic pollutants are introduced. Basic principles of discriminating molecular structures and environmental behaviors of pollutant candidates with regard to the characteristics of persistent organic pollutants are discussed. Technical strategy and advantages of the established analytical frameworks, including quantitative structureproperty relationship model prediction, suspect/non-targeted analysis, and biological effect-directed analysis, are further described. In-depth exploration on occurrence, behavior and effects of novel organic pollutants will play a crucial supportive role in leading the direction of discipline development, improving chemical risk assessment criterions, and revealing the toxicity and hazard mechanisms of environmental pollutants. [ABSTRACT FROM AUTHOR]