Problems with paper entitled The impact of tacrolimus exposure on extrarenal adverse effects in adult transplant recipients.

I read with interest the paper entitled I The impact of tacrolimus exposure on extra-renal adverse effects in adult renal transplant recipients i that was published in the I Journal i (2019, Vol 85, pp. 516-529). Patients receiving tacrolimus have their doses individualized (based upon tacrolimus trough concentration) and this (at least partially) I normalizes i exposure to account for differences in patient factors. [Extracted from the article]