Alterations in biochemical profiles and reproduction performance in postpartum dairy cows with metritis.

The aim of the present study was to evaluate the biochemical profile and reproductive performance in postpartum dairy cows with clinical metritis. The research was carried out using performed on 213 pluriparous lactating cows from two dairy herds in southeast Brazil. Dairy cows were assigned into a group of healthy cows (n = 147) and cows with metritis (n = 66). Blood samples to assess serum albumin, cholesterol, fibrinogen, calcium, gamma‐glutammyltransferase (GGT), aspartate aminotransferase (AST) and β‐hydroxybutyrate (BHBA) concentrations were performed on day 8 ± 2 postpartum. Metritic cows had lower (p <.05) serum albumin, cholesterol and calcium concentration, and higher (p <.05) GGT and AST activity, and BHBA and fibrinogen concentrations when compared to the healthy group. The calving‐to‐conception interval and services per pregnancy were higher in metritic cows (p <.01) than in healthy cows and the conception rate at first service was lower in metric group (p <.01). Variable importance in projection plots demonstrated that cholesterol was the main discriminator between metritic and healthy cows. Our results indicated alterations in the biochemical profile and impaired reproduction performance in metritic cows. [ABSTRACT FROM AUTHOR]