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The Frontal Assessment Battery in RLS patients with and without augmentation.
- Source :
-
Sleep Medicine . Nov2020, Vol. 75, p456-458. 3p. - Publication Year :
- 2020
-
Abstract
- <bold>Objective: </bold>We assessed frontal executive functions in patients with RLS/WED with and without augmentation and compared the results to healthy controls.<bold>Methods: </bold>We recruited 38 patients with RLS/WED. A total of 23 patients were treated with dopaminergic therapy and showed no signs of augmentation and 15 patients had a history of augmentation (AUG). Results were compared to 21 healthy controls. All individuals were assessed by the Frontal Assessment Battery (FAB) and the MMSE. Furthermore, impulsivity was assessed during a semi-structured interview.<bold>Results: </bold>Patients with AUG performed worse in the FAB than healthy controls and RLS/WED patients without AUG (p = 0.001, η2 = 0.201). When we assessed the subtests of the FAB separately, we found a significant difference in the subtest assessing inhibitory control (p = 0.008, η2 = 0.138).<bold>Conclusions: </bold>Our findings suggest an impaired executive function in RLS/WED patients with augmentation compared to RLS/WED patients without augmentation and healthy controls. Long term neuroplastic changes within the prefrontal cortex may be the underlying cause for these results. However, further studies in a larger sample size and with a more extensive neuropsychological test battery are needed to confirm our preliminary results. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RESTLESS legs syndrome
Subjects
Details
- Language :
- English
- ISSN :
- 13899457
- Volume :
- 75
- Database :
- Academic Search Index
- Journal :
- Sleep Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 146997539
- Full Text :
- https://doi.org/10.1016/j.sleep.2020.09.010