外周血中性粒细胞 CD4（nCD4）在白血病合并细菌感染患者检测中的 应用价值.

Observe the accuracy and sensitivity of peripheral blood neutrophil CD4 (nCD4) in the detection of patients with leukemia complicated by bacterial infection, and evaluate its clinical application value. 100 patients with leukemia admitted in our hospital from January 2016 to January 2019 were selected as the research object and included in the study group. Among them, 47 patients with bacterial infection were included in study group Ⅰ, and the remaining 53 patients without bacterial infection were included. Study Ⅱ group, according to the results of blood culture examination, the study Ⅰ components were positive group (n=12) and negative group (n=35). At the same time, 50 cases of healthy physical examination at the same period were screened into the control group; The levels of PCT, CRP and nCD4 were compared, and the diagnostic accuracy and sensitivity of PCT, CRP, and nCD4 in the positive and negative groups were compared. The PCT, CRP, and nCD4 in the study group were higher than those in the control group (all P<0.05), and the PCT, CRP, and nCD4 in the study group Ⅰ were higher than those in the study Ⅱ group (all P<0.05). The intensity was higher than that of the negative group (P<0.05). nCD4 is better than CRP and PCT in the accuracy, sensitivity and specificity of leukocyte bacterial infection. nCD4 has good accuracy and sensitivity in the detection of patients with leukemia complicated by bacterial infection, and combined with PCT and CRP detection can significantly improve the detection accuracy, which can be used as a diagnostic indicator for the diagnosis of leukemia combined with bacterial infection. [ABSTRACT FROM AUTHOR]