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The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics.

Authors :
Woodruff, Trent M.
Shukla, Arun K.
Source :
Trends in Immunology. Nov2020, Vol. 41 Issue 11, p965-967. 3p.
Publication Year :
2020

Abstract

The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a significant global health challenge. A recent study by Carvelli and colleagues now demonstrates the involvement of complement C5a and its receptor C5aR1 in disease progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential therapeutic strategy against COVID-19. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14714906
Volume :
41
Issue :
11
Database :
Academic Search Index
Journal :
Trends in Immunology
Publication Type :
Academic Journal
Accession number :
146614700
Full Text :
https://doi.org/10.1016/j.it.2020.09.008