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Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene- α-D-glucofuranose.
- Source :
-
Acta Crystallographica Section E: Crystallographic Communications . Oct2020, Vol. 76 Issue 10, p1653-sup-5. 9p. - Publication Year :
- 2020
-
Abstract
- Short syntheses to high Fsp³ index natural-product analogues such as iminosugars are of paramount importance in the investigation of their biological activities and reducing the use of protecting groups is an advantageous synthetic strategy. An isopropylidene group was employed towards the synthesis of sevenmembered ring iminosugars and the title compound, C9H15N3O5, was crystallized as an intermediate, in which the THF ring is twisted and the dioxolane ring adopts an envelope conformation: the dihedral angle between the rings is 67.50 (13). In the crystal, the hydroxyl groups participate in O--H (O,O) and O--H N hydrogen-bonding interactions, which generate chains of molecules propagating parallel to the a-axis direction. There is a notable non-classical C--H O hydrogen bond, which cross-links the [100] chains into (001) sheets. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20569890
- Volume :
- 76
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Acta Crystallographica Section E: Crystallographic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 146289705
- Full Text :
- https://doi.org/10.1107/S2056989020012438