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Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer.
- Source :
-
Chemical Communications . 10/4/2020, Vol. 56 Issue 77, p11489-11492. 4p. - Publication Year :
- 2020
-
Abstract
- Novel thiocarbonyl derivatives (NIS and CRNS) with excellent ROS generation abilities are synthesized and studied as potential photosensitizers for one- and two-photon excited photodynamic therapy. In particular, NIS-Me and CRNS display outstanding phototoxicity toward HeLa cells under two-photon excitation (800 nm) with negligible dark toxicity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PHOTODYNAMIC therapy
*CANCER treatment
*PHOTOSENSITIZERS
*HELA cells
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 56
- Issue :
- 77
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 146151279
- Full Text :
- https://doi.org/10.1039/d0cc04644b