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The association of asthma and its subgroups with osteoporosis: a cross-sectional study using KoGES HEXA data.
- Source :
-
Allergy, Asthma & Clinical Immunology . 9/25/2020, Vol. 16 Issue 1, p1-8. 8p. - Publication Year :
- 2020
-
Abstract
- Background: A few studies have reported the association between asthma and osteoporosis. We aimed to analyze the association of asthma and its subgroups with osteoporosis in the Korean adult population. Methods: We used the health examinee (HEXA) data from the Korean Genome and Epidemiology Study (KoGES) obtained between 2004 and 2016. We included 162,579 participants (n = 3,160 with asthma; n = 159,419 controls) who reported their previous histories of asthma and osteoporosis. The participants were categorized into 3 groups based on asthma management: participants who did not need further treatment due to controlled symptoms (well controlled); participants with ongoing treatment (being treated); participants who were not treated even though they had symptoms (not being treated). Multiple logistic regression analyses were used to calculate the adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for osteoporosis. Subgroup analyses for age and sex were conducted. Results: The prevalence of osteoporosis was higher in patients with asthma (13.6%) than in controls (6.8%). In the full-adjusted model, the aORs for osteoporosis were 1.74 (95% CI 1.55–1.94, P < 0.001) in patients with asthma compared to controls. There were consistent findings across the age and sex subgroups. The aORs for osteoporosis were 1.43 (95% CI 1.10–1.86, P = 0.008) in the well-controlled asthma group; 1.55 (95% CI 1.28–1.89, P < 0.001) in the being treated asthma group; and 1.96 (95% CI 1.66–2.31, P < 0.001) in the not being treated asthma group compared to the control group. Conclusion: Asthma was associated with osteoporosis in the Korean adult population. Patients with asthma not being treated showed the highest ORs for osteoporosis. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17101484
- Volume :
- 16
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Allergy, Asthma & Clinical Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 146104663
- Full Text :
- https://doi.org/10.1186/s13223-020-00482-6