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Two Heteroligand Cd(II)-coordination Polymers: Crystal Structures and Anti-Lung Cancer Activity Evaluation.
- Source :
-
Russian Journal of Coordination Chemistry . Sep2020, Vol. 46 Issue 9, p653-661. 9p. - Publication Year :
- 2020
-
Abstract
- Two new Cd(II) containing coordination polymers, namely {[Cd(Dib)(1,4-Ndc)] · H2O}n (I, Dib = 1,4-di(1H-imidazol-1-yl)butane, 1,4-H2Ndc = naphthalene-1,4-dicarboxylic acid) and [Cd(2,2′-Dsb)-(Dpe)-(DMF)(H2O)] (II, 2,2′-H2Dsb = 2,2′-disulfanediyldibenzoic acid, Dpe = (E)-1,2-di(pyridin-4-yl)ethene), have been successfully prepared under the hydrothermal or solvothermal conditions by using the carboxylic acid and N-donor linkers with different functional groups as the co-ligands. Furthermore, the CCK-8 assay was performed to detect the inhibitory effect of these two synthetic complexes on the NCI-H292 lung cancer cell line. The mechanism of the complexes anti-cancer activity was explored with Annexin V-FITC/PI apoptosis detection and western blot assay. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10703284
- Volume :
- 46
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Russian Journal of Coordination Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 145654083
- Full Text :
- https://doi.org/10.1134/S1070328420090080