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Perinatal outcomes of twenty-five human immunodeficiency virus-infected pregnant women: Hacettepe University experience.
- Source :
-
Journal of the Turkish-German Gynecological Association . Sep2020, Vol. 21 Issue 3, p180-186. 7p. - Publication Year :
- 2020
-
Abstract
- Objective: To evaluate perinatal outcomes in human immunodeficiency virus (HIV) infected pregnant women in Turkey. Material and Methods: Maternal characteristics, pregnancy complications, laboratory findings including HIV load, CD4 cell count, CD4/CD8 ratio, neonatal features and final HIV status of the baby were retrospectively analyzed. Results: The sample included 26 singleton pregnancies, from 25 HIV-infected women. The ethnicities were Turkish (n=18), East European (n=4), Asian (n=2) and African (n=2). The majority (76.9%) was aware of their HIV status before becoming pregnant. Four cases (15.3%) were diagnosed during pregnancy and two (7.8%) at the onset of labor. The results for median HIV viral load, CD4 count, and CD4/CD8 ratio at birth were 20 copies/mL (0-34 587), 577/mm³ (115-977), and 0.7 (0.1-1.9), respectively. The HIV viral load rate was 5.5% in eighteen women taking anti-retroviral treatment. The rates of gestational diabetes mellitus, gestational hypertension, intrauterine growth restriction, and preterm delivery were 3.8%, 3.8%, 7.6%, and 8% (numbers are 1;1;2;2), respectively. The mean gestational week at birth was 38 weeks and mean birthweight is 2972±329 g. Two babies were congenitally infected with HIV (infection rate of 8.3%). There was one needle-related accident during surgery. Conclusion: Timely diagnosis of HIV infection during pregnancy is important for preventing mother to child transmission. HIV infected women may give birth to HIV negative babies with the help of a multidisciplinary team, composed of perinatology, infectious diseases, and pediatrics specialists. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13090399
- Volume :
- 21
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of the Turkish-German Gynecological Association
- Publication Type :
- Academic Journal
- Accession number :
- 145631239
- Full Text :
- https://doi.org/10.4274/jtgga.galenos.2019.2019.0033