Nocturnal oxygen therapy as an option for early COVID-19.

• Oxygen supplementation may disrupt virus replication. • Oxygen therapy can improve the antiviral immune response. • An oxygen-rich environment may down-regulate ACE2 expression. • Nocturnal oxygen therapy may delay the progression of COVID-19. There is currently no effective antiviral therapy or immune-based treatment for coronavirus disease (COVID-19). The urgent challenge is to prevent the transition of COVID-19 from mild to severe infection. This paper discussed nocturnal oxygen therapy as a new option for people with COVID-19 under home quarantine. It suggested that nocturnal oxygen therapy in the early stages may be helpful in preventing disease progression by inhibiting the rapid replication of the virus and improving the body's antiviral ability. [ABSTRACT FROM AUTHOR]