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1,3,5-Triazine as core for the preparation of dendrons.
- Source :
-
ARKIVOC: Online Journal of Organic Chemistry . 2020, Vol. 2020, p1-10. 10p. - Publication Year :
- 2020
-
Abstract
- A unique property of 2,4,6-trichloro-1,3,5-triazine (TCT) is its ability to undergoes a nucleophilic aromatic substitution reaction (SNAr) under temperature-controlled conditions. Using a convenient and biologically friendly protocol, mono-substituted s-triazines were treated with excess nucleophiles to obtain tri-substituted triazines in 1 + 2 mode (one nucleophile as the first substitution followed by another nucleophile for the other two positions). The nucleophiles used for this study were phenol, thiol and amine, and the best order of incorporation was phenol or thiol for the first position followed by amine for the last two positions. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NUCLEOPHILIC substitution reactions
*TRIAZINES
*NUCLEOPHILES
Subjects
Details
- Language :
- English
- ISSN :
- 15517004
- Volume :
- 2020
- Database :
- Academic Search Index
- Journal :
- ARKIVOC: Online Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 145452026
- Full Text :
- https://doi.org/10.24820/ark.5550190.p011.245